Madisonville is an unincorporated community in Ralls County, in the U.S. state of Missouri.
[1] The community lies approximately four miles southeast of Center and on the banks of Spencer Creek.
[2] Madisonville was platted in 1836, and named after James Madison Croswaite, the sibling of a first settler.
[3] A post office called Madisonville was established in 1838, and remained in operation until 1906.
This Ralls County, Missouri state location article is a stub.