Built in 1645, the church was constructed by wish of the Queen Regent Christine Marie of France to remember the miraculous rescue from the previous year of a girl from the river.

The painting became such an item of devotion, that this church was built at the site, enlarged in 1779, and furnished with a baptistery in 1807.

Repeated reconstructions have altered the interior, and the church retains only some of the original decoration consisting of the stuccoes attributed to Giovanni Andrea Casella and the cupola frescoes by Bartolomeo Guidobono.

Her Mother, hearing her cries, but unable to see where she was to rescue her, knelt before a nearby shrine built next to the mill, depicting the Annunciation of the Blessed Virgin.

Legend holds a miraculous shaft of light illuminated the spot where her daughter was, and allowed her to be rescued by neighbors.