It was placed on the high altar of Santa Maria in Aracoeli on the Capitoline Hill in Rome,[1][2] the church in which Sigismondo was buried in 1512.

There, in 1802, the painting was transferred from panel to canvas by François-Toussaint Hacquin [3] and restored by Mathias Barthélémy Röser of Heidelberg.

"[4] In 1815, after the Battle of Waterloo, the painting was returned to the Papal States where it was allocated to the Pinacoteca Vaticana of the Vatican Museum.

[5] Rather than sitting under a canopy, of the Umbrian or Florentine style,[2] the Virgin is seated on clouds, embracing Jesus, while surrounded by angels.

Polidoro states that the house of Sigismondo Conti and a fireball are visible in the painting, and that painters at this time used "symbolic meanings that were anything but random".