The 33-storey core of the Madou Plaza Tower was built in just over a month and has been compared as a smaller version of the MetLife Building in New York City.

There is a high voltage transformer in the basement for power, along with a 1360 kW emergency generator added during renovation.

The European Commission bought the building on 13 March 2006, inaugurating it on 19 April when its 1,500 employees moved in.

Based in Madou, as of 2007, were the Directorates-General for Communication, Informatics, and Education and Culture and the Executive Agency for Competitiveness and Innovation.

Staff were previously based on the Axa building on the Robert Schuman Roundabout, which was to be demolished.