Madunice (Slovak: [ˈmaduɲitse]; Hungarian: Vágmedence) is a large village and municipality in Slovakia in Trnava region in Hlohovec District.

North of Madunice are Drahovce, on east Koplotovce, on south Červeník and Leopoldov and on west Pečeňady.

Buses in directions to Piešťany, Trnava, Hlohovec and Veľké Kostoľany stop here.

Close to the town is the main Slovak railway corridor Bratislava – Žilina – Čierna nad Tisou.

Kilometer away from the town center there is a former building of a train stop, nowadays an object of the Slovakian railway company.

The new House of Culture is situated here, with a town hall, post-office, pharmacy, restaurant and more.

In the church there is a side altar made from an oak, under which Ján Hollý composed his poems.

In front of the church is a small park with a larger than life-size statue of Hollý.

An amphitheatre with a snack bar and a stage is located on the east part of Madunice.

After a large fire of Madunice, Ján Hollý left to Dobrá Voda.

In 1993, the book Madunice, 880th anniversary of first literal mention about the town from Karol Kabát was set out.