[4][5] On June 28, 2019, Girl announced a Democratic Party bid for California's 28th congressional district, challenging incumbent Adam Schiff.

[8] She conceded the election on March 27, 2020, when the final results from Los Angeles County races were released, after placing third.

Girl placed second in the June 2022 jungle primary and advanced to the general election, becoming the first Democrat running against Schiff to do so.

[13] As host and producer of the Lyric Hyperion Theatre's drag brunch,[4] she became known for doing satirical impressions of political figures, including Melania Trump, Betsy DeVos, Kellyanne Conway, and Sarah Sanders.

[21] In August 2020, on public comment, Girl endorsed a motion to establish the Los Angeles Commission on Lived Experiences with Homelessness, which would include unhoused people, calling it a “great idea, as long as it’s not conducted in vain,” and emphasizing how the commission would need to be diverse and reflective of the unhoused demographics, with black, brown, Native, and transgender representatives.

[22] Girl announced on June 28, 2019 that they would be challenging Adam Schiff in the March 3, 2020 primary election for California's 28th congressional district.

[23] Girl decided to run as a Democrat, challenging Schiff from the left, and receiving the endorsement of progressive groups, including the local branches of Our Revolution.

[12] She supports Medicare for All, a Green New Deal, abortion rights, federally backed housing vouchers for unhoused individuals, and Education for All.

[33] Girl opposes going to war with Iran,[20] Saudi Arabian-led intervention in Yemen, and increases in defense spending.

[35] In the 2022 Los Angeles mayoral election, Girl endorsed twenty-year old activist Alex Gruenenfelder.

[36] In the 2024 Democratic Party presidential primaries, Girl endorsed the longshot campaign of Marianne Williamson against incumbent President Joe Biden.