[3] Based on the non-fiction book Mafia Inc: The Long, Bloody Reign of Canada's Sicilian Clan by journalists André Cédilot and André Noël, the film stars Marc-André Grondin as Vincent Gamache, a man who gets drawn into Montreal's organized crime underground through his friendship with Giaco Paterno, the son of a major mafia boss.

The cast also includes Sergio Castellitto, Gilbert Sicotte, Mylène Mackay, Tony Nardi and Benz Antoine.

In February 2018 the Quebecor Fund granted $380,000 to support the production of Mafia Inc. and Antigone by Sophie Deraspe (to be divided between the two films).

[6] In May 2018 Telefilm Canada announced it would spend approximately $13 million to fund 10 Quebec films, including Mafia Inc.[7] Principal photography took place in Montreal and then Cuba before completing late in 2018.

[8] According to Metacritic, which sampled six critics and calculated a weighted average score of 64 out of 100, the film received "generally favorable reviews".