Magdalena Wilhelmine of Württemberg (7 November 1677, Stuttgart – 30 October 1742, Karlsburg Castle, Durlach) was a margravine of Baden.

She was the daughter of Duke William Louis of Württemberg and Landgravine Magdalena Sibylla of Hesse-Darmstadt.

In order to strengthen the ties between Baden and Württemberg, she married on 27 June 1697 the Hereditary Prince of Baden and later Margrave Charles William of Baden-Durlach.

When in 1715 Charles William founded his new residence Karlsruhe, he alone moved into the new palace, while his wife remained in the Karlsburg Castle.

After her death she was buried in the margraviate tomb in St. Michael's church in Pforzheim .