The Magill House is a historic hotel located at 100 N. Center St. in Clinton, Illinois.

The hotel was built in order to entice the Illinois Central Railroad to move the headquarters of its Springfield Division to Clinton; the effort was successful, as the railroad moved to Clinton in the late 1870s.

From its construction through the mid-20th century, the hotel was considered the finest in Clinton, and housed both Illinois Central employees and travelers on the railroad.

[2] The hotel was added to the National Register of Historic Places on November 28, 2003.

[1] It is one of two properties on the National Register in DeWitt County, along with the C. H. Moore House.