The plot was owned by Thomas M. Brady, and the community was named for the 3,750 magnolias planted by developers.
Circa 1918 it was renamed "Belgium Street" in honor of a country invaded by Germany in World War I.
By the 1930s political organizations such as the Club Femenino-Chapultepec had been established to protest segregation, promote Mexican-American culture, and provide recreation.
By the World War II period Magnolia Park was considered to be within the East End.
Due to the war, Mexican-Americans in the Southwestern United States were drawn to Houston for jobs, and so the local population increased.
The Magnolia Park YWCA's women hosted the Conferencia de Mujeres por la Raza in 1971.
[2] The Magnolia Park community celebrated the neighborhood's 100 year anniversary on Saturday October 17, 2009.
[14] In the 1970s Papel Chicano, a newspaper that reported on activism in the Houston area, had its offices in Magnolia Park.
In Houston Mexican students by law attended schools designated for Anglo Whites, but the school district opened De Zavala Elementary since area Anglo White parents felt concerned by the rise of the number of ethnic Mexican students in the area.
Circa the 1920s the administrators, who were Anglo Whites, enacted rules prohibiting students from speaking Spanish on the school property.
On December 1, 2023, Greyhound moved its remaining services from Midtown to the Magnolia Park bus stop.
[31] Houston City Council member Robert Gallegos, of District I, stated that Greyhound did not notify him of the timing in advance.
Sylvester Turner, the Mayor of Houston stated that he did not know about the timing of the move until less than 24 hours before Greyhound's announcement.
According to Stephen Fox, who specializes in the history of architecture, this is the city's first ethnic Mexican-oriented public building not made for religious purposes.
Due to financial problems during the Great Depression the society no longer managed the building after 1932.