[4] He is credited with directing the critically acclaimed films Vaastav: The Reality (1999), Astitva (2000) and Viruddh... Family Comes First (2005).

Manjrekar was married to Deepa Mehta, a costume designer, with whom he has two children - Satya and Ashwami.

He was first seen in the Door darshan Marathi series named Kshitij, in which he played a leprosy patient.

He played Chatrapati Shivaji Maharaj in the Marathi film Me Shivajiraje Bhosale Boltoy.

He was a MNS candidate from Mumbai North West in the 2014 Lok Sabha Elections but lost to Gajanan Kirtikar of Shiv Sena.