[2] At the age of 17, Monroe left Santa Barbara and moved to Cabarete in the Dominican Republic to continue training in kiteboarding after spending the previous summer there.

[6] Monroe made her acting debut with a small role on Eleventh Hour, a drama series.

She next appeared in the drama film Labor Day as Mandy, a farm girl who romances with a young man and eventually becomes his wife and the mother of his child.

[14] Writing for Entertainment Weekly, Chris Nashawaty said the film was "airtight" because of "Monroe’s moody teenage authenticity".

[20] In 2017, Monroe starred alongside Timothée Chalamet in the neo-noir coming-of-age film Hot Summer Nights as his girlfriend McKayla.

[23] In 2022, Monroe played Julia in Watcher, the psychological thriller feature directorial debut of Chloe Okuno.

[25] Monroe was cast as Lee Harker in the horror film Longlegs alongside Nicolas Cage.