Mailly-le-Château (French pronunciation: [maji l(ə) ʃɑto]) is a commune in the Yonne department in Bourgogne-Franche-Comté in north-central France.

The lower village is on the left bank of the river Yonne, adjacent to the Canal du Nivernais.

The upper village is noted for its 14th-century fortified castle and the 13th-century church of St Adrian.

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