Main Street Historic District is a national historic district located at Newberry, Newberry County, South Carolina.

The district encompasses 51 contributing buildings in an upper-class neighborhood of Newberry.

They include notable examples of the Italianate, Greek Revival, Neoclassical styles.

[1] Media related to Main Street Historic District (Newberry, South Carolina) at Wikimedia Commons

This article about a property in Newberry County, South Carolina on the National Register of Historic Places is a stub.