Professor Maithree Wickremesinghe (Sinhala: මෛත්‍රී වික්‍රමසිංහ; born 11 August 1964) is the former First Lady of Sri Lanka as the wife of President Ranil Wickremesinghe.

She is a Sri Lankan academic, writer, and professor of English at the University of Kelaniya.

The only child of Senevi B. Wickremasinghe and Shiranee Wickremasinghe (née Bandaratilaka) of Nawala, Koswatte, she attended Musaeus College, a private girls' school in Colombo.

She graduated from King's College London with a BA (Hons) degree in English and went on to complete her MA degree in women's studies at the University of Colombo.

She had gained her Ph.D. degree from the Institute of Education, University of London, specialising in feminist research methodology in Sri Lanka.