[4] She deferred her acceptance to the theatre program at York University in Toronto, which she had initially planned to attend the fall after she graduated high school, so she could shoot the series in Los Angeles.

[13][14] Ramakrishnan created her audition tape at a local library, using her mother's camera, eventually being asked to send four more videos, before having a screen test in Los Angeles and being offered the role.

[36] In May, Ramakrishnan participated in the live-read series Acting for a Cause, appearing as Olivia for a live staged reading of William Shakespeare's play Twelfth Night, to help raise money for a local hospital in Chicago, which was struggling to combat the COVID-19 pandemic.

[39] Ramakrishnan voiced Priya Mangal, an Indian-Canadian mellow, deadpan girl who is one of the protagonist's friends, in the Pixar animated fantasy comedy film Turning Red.

[55][50] In October 2023, Ramakrishnan had a guest voice role on the adult animated sitcom Big Mouth as Marissa, the new love interest and neighbour of the young fictional version of series co-creator Andrew Goldberg.

[58] She will be part of a female ensemble—alongside Shirley Chen, Mckenna Grace, Amelie Zilber, Vivian Wu, and Fang Du—in the satirical drama Slanted, from Tideline, a Fox and MarVista Entertainment label.

[60] Ramakrishnan has also committed to co-lead the Netflix romantic comedy film The Netherfield Girls, a contemporary adaptation of Jane Austen's novel Pride and Prejudice.

[61] In March 2022, Ramakrishnan fronted the spring campaign, "Members Always: Future Together", for clothing retailer American Eagle, alongside Madelyn Cline, Joshua Bassett, Michael Evans Behling, Coco Gauff, and Mxmtoon.

[62][63] In October 2020, Ramakrishnan became a global ambassador for humanitarian organization Plan International Canada, to promote girls and women's rights and gender equality.