The seminary was founded in the Geeraard de Duivelsteen by Cornelius Jansen, the first bishop of Ghent, in accordance with the decrees of the Council of Trent.
In 1623 Bishop Anthonius Triest acquired a new property on Biezekapelstraat, next to Ghent Cathedral, to house the seminary.
This building was heavily renovated and extended in the 18th century, with much of the work commissioned from the architect-contractor David 't Kindt (1699-1770) by Bishop Maximiliaan Van der Noot [Wikidata].
[2] They are now a diocesan activity centre,[3] housing libraries and archives.
[4] In 1925 the seminary was relocated to a purpose-built neo-traditionalist complex on the Reep.