Makhdoom Shahabuddin (Urdu, Saraiki: مخدوم شہاب الدین; born 7 April 1947) is a Pakistani politician and was a member of the National Assembly of Pakistan (February 2008 to May 2013) who has held federal ministerial portfolios for finance, health and textiles.

He is from Mian Wali Qureshian, Rahim Yar Khan, a town in the Saraiki belt[1] of southern Punjab and his political affiliation is with the Pakistan Peoples Party (PPP).

On 19 June 2012, in the aftermath of Yousaf Raza Gilani's conviction and disqualification by the Pakistan Supreme Court on contempt of court charges, Shahabuddin was appointed by the PPP as its candidate for the office of Prime Minister of Pakistan but the nomination was cancelled after a warrant for his arrest was issued by the ANF under suspicious circumstances upon the very day he was nominated.

He is the descendant and successor (sajjada-nasheen) of a famous Sufi saint, Sheikh Makhdoom Hameed-ud-Din Shah Hakim Al-Qureshi Al-Hashmi Suhrawardi and his mausoloem in Mao Mubarak, Rahimyar Khan.

[7] The Supreme Court of Pakistan in its decision to grant him bail observed that it was not merely a coincidence that the warrants for his arrest were issued upon the very day that he was nominated by the PPP.