In 1999, the Exchange moved into the former Garrison Chapel building in Castille Square, Valletta.

This iconic building was built in 1857 on the designs of T. M. Ellis, and was used as a multi-denominational place of worship until 1950.

The former church was then used for entertainment purposes, as a post office and as a naval school, before it was taken over and extensively renovated by the Exchange.

[4] The Exchange is located close to the Office of the Prime Minister at Auberge de Castille and the Upper Barrakka Gardens.

On 23 August 2023, the company formed EuroCTP as a joint venture with 13 other bourses, in an effort to provide a consolidated tape for the European Union, as part of the Capital Markets Union proposed by the European Commission.