Mambo Sinuendo is a studio album released by Cuban performer Manuel Galbán and producer Ry Cooder.

The album was the first number-one album in the Billboard Top Latin Albums chart for Galbán and the second for Cooder (after Buena Vista Social Club in 1998), and won the Grammy Award for Best Pop Instrumental Album at the 46th Grammy Awards.

[1] About the recording of this album, Cooder notes that "Galbán and I felt that there was a sound that had not been explored in a Cuban electric-guitar band that could re-interpret the atmosphere of the 1950s with beauty, agility, and simplicity.

We decided on two electrics, two drum sets, congas and bass: a sexteto that could swing like a big band and penetrate the mysteries of the classic tunes.

Mambo Sinuendo is Cuban soul and high-performance."