The flowers are small but striking, with pale reddish-purple petals, about 12 mm in length and width.

[3] It has been reported in the state of Mexico, at elevations between 700 and 1,250 meters, near the Miguel Alemán hydroelectric system at La Punta, Tingambato, close to the border with Michoacán (at 19°4'N, 100°22'W).

However, this town is approximately 160 kilometers from the border with the state of Mexico, just beyond which the type locality is found.

To prevent this and save space, the cacti nurseryman John Pilbeam recommends growing it upside-down by pulling the stem through a hole in the bottom of a hanging pot.

[6] Mammillaria matudae is legally protected in Mexico by the national list of species at risk of extinction.