The reserve has a high degree of biodiversity and preserving the endangered Atlantis Sand Fynbos vegetation type and the plants and animals that live in it.

[2] The 254 ha (630 acres) area of Mamre Nature Garden protects a rare and valuable piece of the endangered Atlantis Sand Fynbos vegetation type.

Among the many plants to be found here are Protea repens, Gladiolus gracilis ("bloupypie"), Salvia lanceolata, Erica decora.

A settlement was established here in 1701 by the Cape governor, and it was home to a Moravian mission at Louwskloof – now a Provincial Heritage Site.

The September Spring Flower Festival used to be held here, due to this spot's impressive annual display of indigenous wildflowers.