Man-Made Monster is a 1941 American science-fiction horror film directed by George Waggner and produced by Jack Bernhard for Universal Pictures.

The plot resembles The Invisible Ray (1936), The Walking Dead (1936), and two decades later Indestructible Man (1956); that much later feature starred Chaney but was not directly inspired by Man-Made Monster.

[5] Even though it was only a minor box office success, Man-Made Monster proved to be instrumental for Lon Chaney's career; his performance in the lead role helped him win a contract with Universal.

[6][7] While promoting their new star, Universal's publicity department hinted that history was possibly repeating itself, noting that Chaney's first major horror movie role was shot on the same set that was used for his father's well-known production of The Phantom of the Opera.

[10] Man-Made Monster was released on Blu-ray by Scream Factory on June 16, 2020 as part of their Universal Horror Collection series.