[2] William Blood is a man who appears to be immune to all known diseases, and possesses extraordinary resistance to heat and cold – a fact he puts down to his carefree, single life,[a] never committing to any woman, and never being worried by anything.

He makes a living working for medical researchers who are trying to find cures for various diseases and conditions (notably the common cold and seasickness).

Blood never really fits in with the others and, when a £100,000 reward is posted for the first man to land on the Moon, they seek to sabotage his chances and have one of their number selected instead.

When the scientists realise that Leo is the saboteur they use a session in a sensory deprivation chamber to brainwash him into believing he is Blood's best friend.

He finds out his capsule had ejected from the rocket prematurely, landing him in the Australian outback only a few miles from Woomera, and the "alien" turns out to be a man prospecting for uranium.

"With the consent of the British Air Ministry, certain top-secret information – including experiments in rocket propulsion, conditions under tests, and the reactions of bodies to extreme pressure – was made available.

A novelisation of the Man in the Moon screenplay was written by John Foley and published in the UK by Four Square Books, Ltd.