The show follows Jane Snake as she rises the ranks of Wall Street investment firm Lehman Brothers in the years leading up to and during the 2007–2008 financial crisis.

Peter Minuit, who performed the "purchase", is a featured character in the show, mirrored with Richard S. Fuld Jr. of Lehman Brothers.

The name Se-ket-tu-may-qua (translated to Black Beaver in English), which is the name of Luke's mirrored character, is the name of a 19th-century Lenape leader who led Union soldiers hundreds of miles during the Civil War.

[3][4][5] Directed by Kate Whoriskey, its cast featured Tanis Parenteau (Jane/Le-Le-Wa-You), Kimberly Guerrero (Debra/Toosh-Ki-Pa-Kwis-I), Neal Huff (Assistant/Joe), Brandon Oakes (Soldier/Se-Ket-Tu-May-Qua), Andrew Weems (Jonas Michaelius), and Albert Ybarra (Robert/Tamanend).

[7][8] The East Coast premiere of the show, Manahatta ran at the Yale Repertory Theater in New Haven, Connecticut, from January 24 to February 15, 2020.