This made her unable to continue her study in the regular mode and so, she was admitted to Amrit Academy, Kankurgachi, which is a private open-board school.
Manali made her acting debut in the Bengali film Kali Aamar Maa in 1999 where she played the role of a child.
She made her first breakthrough as a model for the Bengali magazine Unish-Kuri, while carrying on her school life.
After making some few photos for the magazine, Manali got a call from Ravi Ojha's production house for working in Bengali television.
Later on, she was cast in the Bengali television serial Neer Bhanga Jhor, which was aired on STAR Jalsha.