[2] Manchester Mayfield station and the surrounding 6.2-acre (25,000 m2) site is the property of London and Continental Railways, the residual government-owned corporation and former partner in Eurostar International.

[6] For example, in the 1957-58 London Midland Region timetable, there were trains to Cheadle Hulme, Buxton, Alderley Edge, Chelford and Stockport on weekdays.

[9] In the London Midland timetable of September 1951, the Pines Express from Bournemouth West is shown as arriving at Mayfield at 4.30pm (16.30) on Mondays to Fridays.

[4] Royal Mail constructed a sorting office on the opposite side of the main line and connected it to Mayfield with an overhead conveyor bridge, which crossed the throat of Piccadilly station.

The depot closed in 1986, following the decision by Parcelforce, Royal Mail's parcels division, to abandon rail transport in favour of road haulage.

The building has remained disused since then,[13] with the tracks into Mayfield removed in 1989, as part of the remodelling of the Piccadilly station layout.

[15] The location of the proposed platforms was also criticised, as it would entail "a long walk for passengers wishing to interchange with other terminating rail services at Manchester Piccadilly or access the city centre.

[13] The future of the former railway station has yet to be decided and Mayfield Manchester were, as of April 2008, said to be in talks with its owners, BRB Residuary.

[14][20] In a proposal floated in May 2009, the Labour government were said to have earmarked the site as the location of a 700,000 sq ft (65,000 m2) "super-campus" to house 5,000 civil servants.

[21][22] In November 2013, a planning application was made for conversion of the station to an arts and entertainment venue[23][24] with a maximum capacity of up to 7,500 people.