It is bordered by Mylapore in the north, Santhome (and MRC Nagar) in the east and RA Puram in the south and in the west.

Due to its proximity to the temple dense Mylapore, Mandaveli is home to a large number of Brahmins.

Mandavelipakkam is seen as a residential and business area located between Santhome (which is home to the San Thome Basilica) to the north and Adyar to its south.

Several old buildings are being demolished to make way for newer structures like the Kabali Theatre, which is located near Mandaveli bus stand has been changed into a big apartment.

The Sun TV Network (located in the Murasoli Maran Towers),[2] TVH Bellicia Tower, The India Cements Building and iconic Mayor Ramanathan Chettiar Marriage Hall[3] and Conference Centre are a few important buildings located here.