Mandres-les-Roses (French pronunciation: [mɑ̃dʁ le ʁoz] ⓘ) is a commune in the southeastern suburbs of Paris, France.

The palaeographer and archivist Robert Marichal (1904–1999) was born in Mandres-les-Roses.

The average annual rainfall is 698.3 mm (27.49 in) with December as the wettest month.

The temperatures are highest on average in July, at around 20.2 °C (68.4 °F), and lowest in January, at around 4.5 °C (40.1 °F).

Mandres-les-Roses is served by no station of the Paris Métro, RER, or suburban rail network.