The story revolves around Kiefer (Vhong Navarro), a normal guy who lives a quiet life until he goes through bizarre experiences, seeing ghosts and evil spirits.

With this, his mother Milagros (Jacklyn Jose) is forced to tell him the truth that he is Mang Kepweng's son.

With Kiefer's determination to know more about his roots and how he is connected to the paranormal occurrences he is experiencing, he travels to the provinces meeting his half-brother Zach (James Blanco), a successful doctor who cannot cure his wife's Via (Sunshine Cruz) mysterious illness.

Zach later revealed that their late father Mang Kepweng (Chiquito) left a scarf which gives a healing power to whoever wears it.

[4] A sequel was announced on August 20, 2019, on Twitter entitled Mang Kepweng: Ang Lihim ng Bandanang Itim and part of the 2020 Metro Manila Film Festival and to be released on December 25, 2020.