Manistee is an unincorporated community in Monroe County, Alabama, United States.

The Manistee Mill Company built a spur track to connect the sawmills of Manistee with the Louisville & Nashville Railroad in Repton and named it the Manistee & Repton Railway.

[2] Amasa Coleman Lee, father of Harper Lee, served as financial manager for a Monroeville law firm's interests in the Manistee & Repton Railway.

[3] A post office was operated in Manistee from 1892 to 1912.

This Monroe County, Alabama state location article is a stub.