Provincial Road 325 (PR 325) is a 129.0-kilometre-long (80.2 mi) east–west highway in the Interlake Region of Manitoba, Canada.

PR 325 begins a few kilometres east of The Narrows in the Rural Municipality of West Interlake in the Oakview community, at a junction with PTH 68 (Northern Woods and Water Route).

Leaving Ashern, the pavement transitions to gravel at an intersection with Cook Road and the highway continues on through forested areas and passes through a section of the Rural Municipality of Grahamdale.

Joining a concurrency with PTH 17, it becomes paved once more and the pair head for a short distance before making a sharp curve to the east to pass through the town of Hodgson, where they cross a creek twice.

After passing through remote woodlands, some of which are portions of Moose Creek Provincial Forest, the highway comes to an end near the shores of Lake Winnipeg at an intersection with PR 234, just north of Washow Bay.