PR 478 begins in the Municipality of Russell-Binscarth at the Saskatchewan border, with the highway continuing east towards Gerald and Esterhazy as Hwy 22.

Rising in elevation back out of the valley, the highway passes just to the north of the Gambler First Nation before entering Binscarth, crossing a railway as it makes an immediate right onto 1st Avenue in downtown.

After curving onto Government Road, PR 478 travels through neighbourhoods along the south side of to town before coming to an intersection with the Yellowhead Highway (PTH 16/PTH 83).

[1] With the transition from asphalt to gravel, the highway heads east to leave Binscarth and travel through farmland, going through some switchbacks to enter the Rural Municipality of Riding Mountain West and changes cardinal directions from east–west to north–south.

[2] The highway then travels through rural farmland for several more kilometres before coming to and end at an intersection with PR 264 near Cracknell.