Manlius is a village in Bureau County, Illinois, United States.

[5] According to the 2021 census gazetteer files, Manlius has a total area of 0.32 square miles (0.83 km2), all land.

[6] As of the 2020 census[8] there were 298 people, 131 households, and 81 families residing in the village.

There were 164 housing units at an average density of 514.11 per square mile (198.50/km2).

35.88% of all households were made up of individuals, and 16.79% had someone living alone who was 65 years of age or older.