In July 1781, during the Revolutionary War, British Lieutenant Colonel Banastre Tarleton, tasked by Lord Charles Cornwallis with raiding Southside Virginia and destroying "stores of any kind" that could be used by the Continental Army, burned a granary at Mannboro before striking Amelia Court House.

Wise, recounts a clash between his grandfather's troops and those of Union commander Philip Sheridan at Deep Creek near Mannboro.

[4] Depleted Confederate forces, hoping to reach a promised delivery of badly needed rations at the Court House rail depot, had just fought an inconclusive battle at Namozine Church, 6 miles east, on April 3.

[5] During the early 20th century, the Rosenwald School project was a collaborative effort that built thousands of facilities across the South primarily for the education of African American children.

As late as 1967, after desegregation, a campus named Mannboro School, alternatively called Amelia Academy,[6] continued to operate on Route 612.