Mansion House is a historic home located at McDowell, Highland County, Virginia.

It was built in 1851, and is a two-story, three-bay, L-shaped brick dwelling in the Greek Revival style.

Also on the property are a contributing frame shed, and the sites of a log kitchen structure and outbuilding.

The house served as an American Civil War hospital in the time around the Battle of McDowell on May 8, 1862.

This article about a property in Highland County, Virginia on the National Register of Historic Places is a stub.