Manuel Díaz Rodríguez (28 February 1871 – 24 August 1927), was a Venezuelan writer, journalist, physician, diplomat and politician.

He served as director of Higher Education and Fine Arts at the Ministry of Education in 1911, Minister of Foreign Affairs between 1913 and 1914, Senator for the Bolívar state in 1915, Minister of Development in 1916, Minister Plenipotentiary of Venezuela in Italy from 1919 until 1923, Head of Government of the states Nueva Esparta (1925) and Sucre (1926).

He died in New York City, where he had traveled for treatment of a throat ailment, in 1927.

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