He came from an old Castilian family from Province of Ávila,[1] the son of composer, Eleodoro Ortiz de Zárate and of Matilde Pinto Benavente.
There, he became part of the growing gathering of artists in the Montparnasse Quarter, making friends with Amedeo Modigliani, Pablo Picasso, Léonard Foujita, and some of the other future greats of the art world.
[3][4] Manuel Ortiz de Zárate studied at the École des Beaux-Arts in Paris, developing his modernist skills in the painting of still lifes and landscapes.
[4] Between 1920 until 1940, Ortiz de Zárate showed his work at the Salon d’Automne, an annual art exhibition in Paris, France.
[5] Together with Camilo Mori and other artists from Chile, Manuel Ortiz de Zárate helped found the Grupo Montparnasse.