Manuel Osorio Manrique de Zúñiga is a large full-length portrait in oil painted in 1787–88 by the Spanish artist Francisco Goya.

This painting, from 1787–88, depicts Altimira's youngest son, Manuel, who was born in April 1784 and died at age eight on June 12, 1792.

Bernstein based parts of the stage design for his 1924 play La Galerie des glaces on the painting, and then sold it to the art dealer Joseph Duveen in 1925 for 450,000 francs and £9,000.

In 1926, Kathryn Bache Miller fell in love with this painting while at the Paris art gallery of Joseph Duveen.

[8] From April 22 to August 3, 2014, the museum reunited Manuel with his parents in the exhibit Goya and the Altamira Family.