[2] Born in 1914 in Morenci, Arizona, in 1917 his family moved to Los Angeles where Perez later attended high school.

[9] Among the cartoons he animated were those featuring Bugs Bunny, Daffy Duck, Porky Pig, Elmer Fudd, Tweetie and Sylvester, Quick Draw McGraw, the Pink Panther,[11] The Peanuts specials A Charlie Brown Christmas and He's Your Dog, Charlie Brown, Wile E. Coyote and the Road Runner, Doctor Dolittle, The Cat in the Hat, Fritz the Cat, where he infamously animated Fritz and three girls in the bathtub for two thousand drawings (half a minute), and Plastic Man, among many others.

[6][12][13] A member of the labor union The Screen Cartoonists Guild, Perez was one of the animators involved in the 'Looney Tunes Lock Out' of 1941, when Leon Schlesinger, who had been producing cartoons for Warner Bros. Cartoons since the mid-1930s, locked out those animators who had joined the Guild, including Perez.

At the mention of Friz' name he said these words, with a tense smile, that I'll never forget: "You know, I worked so long for him.

I got to hate that little guy ..."[10]In his later years, Perez worked on Journey Back to Oz (1971); the animated version of The Lord of the Rings (1978),[9] The Plastic Man Comedy/Adventure Show (1979),[10] and The Bugs Bunny/Road Runner Movie (1979).