Manuel Antonio Rojo del Río y Vieyra (September 24, 1708 – January 30, 1764)[1] was a Mexican (originally Spanish Criollo) friar who served as the 16th Archbishop of Manila and was Governor-General of the Philippines at the commencement of the 1762–1764 British occupation of the Philippines.

[2] On May 31, 1759, the death of Governor-General Pedro Manuél de Arandía left the position vacant.

Bishop Miguel Lino de Ezpeleta of the Archdiocese of Cebu succeeded him as well as becoming acting Archbishop of Manila.

In 1761, a royal decree from Spain ruled that Rojo del Río replace Ezpeleta to become Governor-General.

"Albeit he had the gift of knowledge, he had no judgment, especially in matter military, to which he was hostile and negative, since this was an area outside his profession and character."