[1] At the Colegio de San Gregorio, due to his brilliant participation in the discussions of the Academy of Jurisprudence, Romero Rubio received various offers to occupy positions in the government; however, he did not accept these invitations, preferring to finish his studies.

For this reason, Manuel Romero Rubio and Ignacio Mariscal, among other students, became the main organizers of the Club Político el Águila, which emerged as a protest, and which was joined by several figures who later occupied high positions in Mexican politics.

[1] On January 11, 1854, Romero Rubio obtained his law degree from the Colegio de San Gregorio, and enrolled before the National Association Bar with the financial support of José Urbano Fonseca Martínez.

[1][2] In 1854, being 26 years old, Manuel Romero Rubio joined the Plan of Ayutla, aimed at removing conservative, centralist President Santa Anna government[1] and, with Miguel Buenrostro, he held a first meeting with Benito Juárez as the representative of the Liberal clubs in Mexico City.

[1] After Santa Anna's resignation in 1855 by the Ayutla Revolution, the Constituent Congress of 1856-1857 was established, where Manuel Romero Rubio – without having proposed a candidacy – was elected alternate deputy by the State of Mexico thanks to his excellent reputation  as a magistrate in the Tulancingo court.

[2] At the end of March 1858, the new conservative government of Félix María Zuloaga apprehended Romero Rubio, Riva Palacio and other liberals who were transferred to the dungeons of the ex-Acordada, from where they corresponded with their allies, to stay informed about the events of the Reform War.

[2] On November 20, 1858, when he was released along with the rest of the ex-Accorda political prisoners, Manuel Romero Rubio was appointed head of the Huastecas forces of the liberal army, and joined the front of General Juan J. de la Garza in Tamaulipas, who named him second in command of his division.

Despite belonging to the Lerdistas group, with the Juaristas victory in the elections of 1867, Romero Rubio was named President of the Chamber of Deputies in 1870, and his house was consolidated as one of the most important political meeting places of the time.

[2] Romero Rubio was recognized for his extraordinary ability to negotiate, so his adherence to the Porfirian project offered the possibility of legitimizing the government of Díaz by nullifying one of the main axes of dissent and allowing him a strategic alliance that gave him the backing of a experienced circle of Mexican politicians and intellectuals.

[1] The competences of the Secretary of the Interior under the leadership of Manuel Romero Rubio covered a wide range of powers that, due to their enormous social and political weight, were essential for the constitution of the Porfirian hegemony.

[1] The success of Manuel Romero Rubio's policies was recognized by his contemporaries, and helped him position himself as a fundamental element within the heterogeneous Porfirian cabinet, thanks to his immense capacity for negotiation and conciliation,[1] becoming for this reason the right hand of Porfirio Díaz.

With a manifesto written by Justo Sierra, multiple calls for parades and demonstrations in favor of Díaz, and the creation of Porfirista clubs throughout the country, the Liberal Union managed to successfully attract all kinds of social and political strata that adhered to its cause.

With this impressive maneuver, Romero Rubio managed to transform the political environment –which did not originally favor Díaz–, and consolidate him before public opinion as the only figure capable of continuing the progressive project and maintaining the country's stability.