The Manufacturing and Wholesale Historic District is a nationally recognized historic district located adjacent to the central business district of Burlington, Iowa, United States.

It was listed on the National Register of Historic Places in 2012.

[2] The tracks of the former Chicago, Burlington and Quincy Railroad bisect the district and contributed to its development.

The Romanesque Revival John Blaul and Sons Wholesale Grocery building is the only building that wasn't built in a utilitarian form with only general stylistic influences.

The area largely housed manufacturing and wholesale businesses into the 1970s and 1980s.