A convent of Augustinian canons (monasterium rosarum) was probably established around 960, when the area became part of the Imperial March of Verona.

The monastery church dedicated to Saint Peter was consecrated in 1070; it was elevated to the rank of an abbey by the Aquileia patriarch Ulrich of Eppenstein about 1090.

At the time, the premises were settled with Benedictine monks descending from Millstatt Abbey in Carinthia, where Ulrich's brother Liutold was duke.

Part of the Kingdom of Italy from 1866, Manzano was the site where during World War I, from 29 July 1917, the first Arditi units of the Royal Italian Army were formed and trained.

[3] Rosazzo Abbey was heavily damaged by the 1976 Friuli earthquake, but restored under the auspices of the Udine archbishop Alfredo Battisti.