She began her career singing as a duo with her sister, but her most memorable works were as a solo singer after their duet broke up.

[1] She began singing with her sister Avelina Landín in 1935 at parties and private functions and they were hired for their first professional work by the radio stations XEYZ and XEFO the following year, under the name "Pyrite and Jade".

[4][6] Then after the break-up, in 1943 she recorded duets for the Coca-Cola Company with tenor, Néstor Mesta Chaires, which included "Bésame mucho", "Delirio", "Enamorado de ti", "Luna de Plata", "Muchos besos", "Que voy hacer sin ti" and "Vivirás en mí".

[4] Her interpretation of "Lost Love" has become the second most-played song in the history of Mexican broadcasting[3] and earned her the title "Queen of the bolero".

[2] Besides her interpretation of "Amor perdido", Landín's most successful recordings included "Aunque tengas razón" (1946) by Consuelo Velázquez, "Déjame en paz" (1946) by Luciano Miral, "Dos almas" (1946) by Don Fabián; "Injusticia" (1946) by Pablo Beltrán and "Será por Eso" (1946) by Consuelito Velázquez.

She subsequently successfully toured throughout Mexico, the Caribbean, Central and South America as well as in Los Angeles, San Francisco and Spain, working with a variety of artists.

In 1955 a production in celebration of the thirteenth anniversary of La Voz Dominicana TV teamed her with Luis Arcaraz [es], Fernando Fernández, María Elena Marqués, Amalia Mendoza, María Antonieta Pons, Flor Silvestre and Nicolás Urcelay.