James Kalacherry (20 April 1892 – 27 October 1949) was an Indian educationalist and bishop of the Syro-Malabar Catholic Church, taking charge of the Diocese of Changanassery.

He was ordained priest at the age of 27 on 19 April 1919, and as Rev Dr James Kalacherry, served as lecturer in logic at St. Berchmans College, Changanassery, Kottayam, Kerala.

[2] On 19 May 1930 Bishop Kalacherry presided over the ceremony when Sister Alphonsa joined the Franciscan Clarist Congregation at St. Mary's Forane Church, Bharananganam.

Bishop Kalacherry founded Assumption College, in central Travancore on 12 August 1949, providing tertiary education for women.

[5] He died in office at the age of 57 on 27 October 1949 and was buried at St. Mary's Cathedral in Changanassery, which was his own parish.