[10] Mönchengladbach's senior side were seemingly failing in their efforts to avoid relegation, and on 14 February 2011, manager Michael Frontzeck was replaced by Lucien Favre, with the team rooted to the bottom of the Bundesliga, having accumulated only 16 points after 22 match days.

Ter Stegen's progress for the reserve team had not gone unnoticed by the supporters, and the new manager was inundated with demands to start the young prodigy in the league.

During this run, he shot to prominence with a last-man-standing display against eventual champions Borussia Dortmund, making a string of world-class saves as Mönchengladbach secured a famous 1–0 victory.

[citation needed] During the summer transfer window, Bayern Munich had succeeded in their drawn-out pursuit of Schalke 04's captain Manuel Neuer.

The match did not go the way the pundits predicted, however, with Ter Stegen producing yet another inspired display whilst his counterpart Neuer made the error that condemned Bayern to a 1–0 defeat.

[citation needed] After the departures of Reus to Borussia Dortmund and Dante to Bayern Munich, Ter Stegen emerged as Mönchengladbach's main star for the season.

[19] Due to this injury, Barcelona manager Luis Enrique made Bravo the starting league goalkeeper, where he would go on to win the Zamora Trophy.

"[28] Ter Stegen picked up injuries at the start of the season, due to which he missed the Supercopa de España and league matches.

[29] On 13 September 2016, Ter Stegen gave away and saved a penalty from Moussa Dembélé which kept the score at 1–0 and which eventually led to a 7–0 victory for Barcelona against Celtic in the UEFA Champions League.

[30] On 2 October 2016, Ter Stegen had a poor performance when he made two crucial mistakes, which cost Barcelona the match, as they eventually went on to lose 4–3 against Celta Vigo.

[37] On 14 October 2017, Ter Stegen made some critical saves, including two well-placed shots from Antoine Griezmann of Atlético Madrid, en route to a 1–1 draw at the newly-rebuilt Wanda Metropolitano, preserving Barcelona's unbeaten record in the 2017–18 La Liga season.

[41] The result was good enough to secure a draw and a first place position in Group D, qualifying Barcelona to the 2017–18 UEFA Champions League knockout phase.

[44] Ter Stegen won his fourth La Liga title with Barcelona, and reached the semi-finals of the 2018–19 UEFA Champions League, where his team was eliminated from the competition after losing 3–4 on aggregate against Liverpool, including a 0–4 loss at Anfield in the second leg.

[51] After the end of the previous season, it was announced that Ter Stegen underwent a successful knee surgery which would be keeping him out of the team for over two months.

On 20 October, Ter Stegen extended his contract with Barcelona that would keep him at the club till 30 June 2025, with a buy-out clause of €500 million.

Leading a Barcelona defence bolstered by the signings of Jules Koundé and Andreas Christensen, Ter Stegen won his first Zamora Trophy for conceding just 18 goals in 38 appearances.

[61] On 27 June 2015, ter Stegen conceded five goals in Germany U21s' match against Portugal U21 in the semi-finals of the UEFA European Under-21 Championship in Czech Republic.

[62] ter Stegen was rewarded for his performances by Joachim Löw, who called him up to Germany's provisional squad for UEFA Euro 2012, but did not make the final 23-man.

[63] He stopped a penalty from Lionel Messi in his second international match in a 1–3 loss against Argentina on 15 August, immediately after coming on following Ron-Robert Zieler's sending off.

[69] In September 2019, Ter Stegen engaged in a minor war of words with Manuel Neuer over the number one goalkeeper spot for Germany.

[70][71] In May 2021, Ter Stegen was omitted from Germany's UEFA Euro 2020 squad after opting to undergo surgery to treat an injury to the patellar tendon in his right knee.

[76] In 2020, former Spain and Barcelona goalkeeper Salvador Sadurní noted that Ter Stegen's style of play is very similar to that of his German compatriot Manuel Neuer.