Marc Handley Andrus (born October 20, 1956) is an American bishop of the Episcopal Church (Anglican Communion).

After receiving his master's degree, Andrus went to work as a regional planner for the Accomack-Northampton Planning District Commission on Virginia's Delmarva Peninsula.

Early in his tenure as Bishop of California, Andrus co-chaired a community coalition that paved the way for the rebuilding of St. Luke’s Hospital, San Francisco.

While bishop of California, Andrus became a member of the We Are Still In Leaders' Circle, a diverse group of ambassadors for American climate action.

In October 2024, The Episcopal Church restricted Andrus' ministry to investigate an allegation of having an inappropriate relationship with an adult.