[2] Dzama works in multiple disciplines to bring his cast of human figures, animals, and imaginary hybrids to life, and has developed an international reputation and following[citation needed] for his art that depicts fanciful, anachronistic worlds.

He also provided the cover art for literary critic Sianne Ngai's 2005 book Ugly Feelings, published by Harvard University Press.

In 2016, Dzama created the costume and stage design for the New York City Ballet's The Most Incredible Thing, a performance based on Hans Christian Andersen's fairy tale.

[6] Dzama has been the subject of solo exhibitions at the Musée d'Art Contemporain de Montréal (2010)[7][8] and Pinakothek der Moderne, Munich (2008).

In May 2016 at the Labs Gallery in Bologna was presented an exhibition of his works entitled "Masked Tales", in which also exposed an Italian artist Vanni Cuoghi.