Marcella Di Folco (7 March 1943 – 7 September 2010) was an Italian LGBT rights activist, actor, and politician.

In her film appearances, played in male characters before transition, she is credited as Marcello Di Falco.

She was the first open trans woman to hold a political public office in the world.

In 2024 her documentary biography has been included in Disobedience Archive, a Marco Scotini project dealing with LGBT issues, invited by Curator Adriano Pedrosa at Foreigners Everywhere art exhibition at 60th Venice Biennale.

This biography of an activist for lesbian, gay, bisexual, transgender, queer rights is a stub.